The Saticoy Southern Pacific Railroad Depot is located in the unincorporated community of Saticoy at 11220 Azahar Street.

The depot, built in 1887, was designated Ventura County Historic Landmark no. 176 in May 2016. It was listed on the National Register of Historic Places in 2018.

The depot was built by the Southern Pacific Railroad along the line that was being constructed from Los Angeles to Ventura in 1887. The original town of Saticoy was laid out near the new depot. Its name comes from the Chumash village of Sa’aqtik’oy. 

The Saticoy Depot served rail that traveled through the Santa Clara Valley between Saugus to Ventura County. It was one of 14 Southern Pacific Railroad Depots in Ventura County - the others were Oxnard, Santa Susana, Santa Paula, Fillmore, Piru, Ojai, Camarillo, Moorpark, Sespe, Camulos, Somis, Montalvo and downtown Ventura. Only six of these remain today.